Cspg4tm1.1(cre/ERT2)Fki
Targeted Allele Detail
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Symbol: |
Cspg4tm1.1(cre/ERT2)Fki |
Name: |
chondroitin sulfate proteoglycan 4; targeted mutation 1.1, Frank Kirchhoff |
MGI ID: |
MGI:5566862 |
Synonyms: |
NG2-CreERT2, NG2ct2 |
Gene: |
Cspg4 Location: Chr9:56772388-56807154 bp, + strand Genetic Position: Chr9, 30.32 cM
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Alliance: |
Cspg4tm1.1(cre/ERT2)Fki page
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Germline Transmission: |
Earliest citation of germline transmission:
J:209130
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase) |
Inducer: |
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tamoxifen |
Mutations: |
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Insertion, Intragenic deletion
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Cspg4tm1.1(cre/ERT2)Fki expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A cre/ERT2 open reading frame and Frt-flanked neomycin cassette replaced exon 1 of the Cspg4 (NG2) locus following homologous recombination in E14.1 ES cells. The neo cassette was deleted by crossing mice to flp expressing mice. No Cspg4 protein is detected in brain lysates.
(J:209130)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Cspg4
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cspg4 Mutation: |
102 strains or lines available
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Original: |
J:209130 Huang W, et al., Novel NG2-CreERT2 knock-in mice demonstrate heterogeneous differentiation potential of NG2 glia during development. Glia. 2014 Jun;62(6):896-913 |
All: |
18 reference(s) |
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