Cyp4f18^tm1.2Pchr
Targeted Allele Detail

Summary

• Symbol: Cyp4f18^tm1.2Pchr
• Name: cytochrome P450, family 4, subfamily f, polypeptide 18; targeted mutation 1.2, Peter Christmas
• MGI ID: MGI:5566681
• Synonyms: Cyp4f18 floxed
• Gene: Cyp4f18 Location: Chr8:72742326-72763470 bp, - strand Genetic Position: Chr8, 34.67 cM, cytoband C1
• Alliance: Cyp4f18^tm1.2Pchr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212489
• Parent Cell Line: D1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Flp recombinase expression was used to excise an FRT-flanked neo cassette from intron 9, leaving a loxP site in intron 7 and a single FRT site followed by a second loxP site in intron 9. (J:212489)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cyp4f18 Mutation: 38 strains or lines available

References

• Original: J:212489 Winslow V, et al., Altered leukotriene B4 metabolism in CYP4F18-deficient mice does not impact inflammation following renal ischemia. Biochim Biophys Acta. 2014 Jun;1841(6):868-79
• All: 1 reference(s)