Gt(ROSA)26Sor^tm1(Ago2)Ans
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(Ago2)Ans
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Anne Schaefer
• MGI ID: MGI:5563808
• Synonyms: Rosa-Stop^fl-Flag-Ago2
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(Ago2)Ans page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165750
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^tm1(Ago2)Ans expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ago2 (MGI:2446632)

• Mutation details: A construct consisting of a floxed neo-stop cassette, FLAG-HA2-Ago2 sequence, and an IRES-EGFP cassette was inserted via homologous recombination. (J:165750)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1058 strains or lines available

References

• Original: J:165750 Schaefer A, et al., Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. J Exp Med. 2010 Aug 30;207(9):1843-51
• All: 4 reference(s)