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Chemically induced Allele Detail
Symbol: Rbm5sda
Name: RNA binding motif protein 5; spermatid differentiation arrest
MGI ID: MGI:5563424
Synonyms: Joey-RSA
Gene: Rbm5  Location: Chr9:107617694-107648228 bp, - strand  Genetic Position: Chr9, 59.07 cM
Alliance: Rbm5sda page
Spermatid differentiation arrest, germ cell sloughing and apoptosis lead to sterility in the Rbm5sda/Rbm5sda males

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  C57BL/6
Project Collection: APF ENU Mutagenesis
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
Mutation detailsENU mutagenesis induced a G to C point mutation at position 940 on cDNA (ENSMUST00000035199) in exon 10 that results in the amino acid substitution of Arginine to Proline at position 263 (R263P) within the second RNA recognition motif (RRM2). Genetic complementation data suggest that the R263P mutation results in a loss-of-function allele. (J:104190, J:223049)
Inheritance:    Recessive
Generation of the Rbm5sda allele
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Rbm5 Mutation:  51 strains or lines available
Original:  J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory