About   Help   FAQ
Rbm5sda
Chemically induced Allele Detail
Summary
Symbol: Rbm5sda
Name: RNA binding motif protein 5; spermatid differentiation arrest
MGI ID: MGI:5563424
Synonyms: Joey-RSA
Gene: Rbm5  Location: Chr9:107617694-107648228 bp, - strand  Genetic Position: Chr9, 59.07 cM
Alliance: Rbm5sda page
Spermatid differentiation arrest, germ cell sloughing and apoptosis lead to sterility in the Rbm5sda/Rbm5sda males

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6
Project Collection: APF ENU Mutagenesis
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a G to C point mutation at position 940 on cDNA (ENSMUST00000035199) in exon 10 that results in the amino acid substitution of Arginine to Proline at position 263 (R263P) within the second RNA recognition motif (RRM2). Genetic complementation data suggest that the R263P mutation results in a loss-of-function allele. (J:104190, J:223049)
Inheritance:    Recessive
Generation of the Rbm5sda allele
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Rbm5 Mutation:  51 strains or lines available
References
Original:  J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory