Hes5^tm2Imayo
Targeted Allele Detail

Summary

• Symbol: Hes5^tm2Imayo
• Name: hes family bHLH transcription factor 5; targeted mutation 2, Itaru Imayoshi
• MGI ID: MGI:5562881
• Synonyms: Eluc-Hes5, Hes5^{tm1(Eluc)Imayo}, Hes5^tm3.1Kag
• Gene: Hes5 Location: Chr4:155045380-155046828 bp, + strand Genetic Position: Chr4, 86.01 cM
• Alliance: Hes5^tm2Imayo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203419
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A luciferase (Eluc) expression cassette was inserted in frame in the 5' region and an FRT flanked pgk-neo cassette was inserted in the first intron. Flp mediated recombination removed the neo cassette. Reporter expression is similar to endogenous gene expression. (J:203419)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hes5 Mutation: 16 strains or lines available

References

• Original: J:203419 Imayoshi I, et al., Oscillatory control of factors determining multipotency and fate in mouse neural progenitors. Science. 2013 Dec 6;342(6163):1203-8
• All: 1 reference(s)