Cpeb3^tm1.1Yshu
Targeted Allele Detail

Summary

• Symbol: Cpeb3^tm1.1Yshu
• Name: cytoplasmic polyadenylation element binding protein 3; targeted mutation 1.1, Yi-Shuian Huang
• MGI ID: MGI:5562640
• Synonyms: fCPEB3
• Gene: Cpeb3 Location: Chr19:36998691-37186000 bp, - strand Genetic Position: Chr19, 32.08 cM
• Alliance: Cpeb3^tm1.1Yshu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202741
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked PGK-neo cassette is inserted into intron 1, followed by loxP-flanked exon 2. Flp-mediated recombinase removed the neo cassette, resulting in a loxP-flanked exon 2 allele. (J:202741)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cpeb3 Mutation: 34 strains or lines available

References

• Original: J:202741 Chao HW, et al., Deletion of CPEB3 Enhances Hippocampus-Dependent Memory via Increasing Expressions of PSD95 and NMDA Receptors. J Neurosci. 2013 Oct 23;33(43):17008-22
• All: 4 reference(s)