Gt(ROSA)26Sor^{tm407(H1/tetO-RNAi:Large)Arte}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm407(H1/tetO-RNAi:Large)Arte}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 407, TaconicArtemis
• MGI ID: MGI:5562445
• Synonyms: Large^KD
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm407(H1/tetO-RNAi:Large)Arte} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206057
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Knockdown)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm407(H1/tetO-RNAi:Large)Arte} involves 1 genes/genome features (Large1) View all
• Mutation details: The targeting construct introduced into the locus a short hairpin RNA (shRNA) against Large under the control of the H1-tetO promoter. (J:206057)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:206057 Goddeeris MM, et al., LARGE glycans on dystroglycan function as a tunable matrix scaffold to prevent dystrophy. Nature. 2013 Nov 7;503(7474):136-40
• All: 1 reference(s)