Dzip1tm1.1Blnw
Targeted Allele Detail
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Symbol: |
Dzip1tm1.1Blnw |
Name: |
DAZ interacting protein 1; targeted mutation 1.1, Baolin Wang |
MGI ID: |
MGI:5557987 |
Synonyms: |
Dzip1deltaE1-2 |
Gene: |
Dzip1 Location: Chr14:119112932-119162872 bp, - strand Genetic Position: Chr14, 62.56 cM, cytoband E4
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Alliance: |
Dzip1tm1.1Blnw page
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The neural tube and somites are underdeveloped in Dzip1tm1.1Blnw/Dzip1tm1.1Blnw embryos
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:207249
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Parent Cell Line: |
W4 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Not Applicable) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 2 and 3 were replaced with a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. Western blot analysis confirmed the expression of a truncated protein in embryos.
(J:207249)
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Generation of the Dzip1tm1.1Blnw allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dzip1 Mutation: |
37 strains or lines available
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Original: |
J:207249 Wang C, et al., Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis. J Biol Chem. 2013 Oct 11;288(41):29518-29 |
All: |
1 reference(s) |
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