Tas2r131^tm1Uboe
Targeted Allele Detail

Summary

• Symbol: Tas2r131^tm1Uboe
• Name: taste receptor, type 2, member 131; targeted mutation 1, Ulrich Boehm
• MGI ID: MGI:5557981
• Synonyms: Tas2r131^BLiG
• Gene: Tas2r131 Location: Chr6:132933875-132934807 bp, - strand Genetic Position: Chr6, 64.03 cM
• Alliance: Tas2r131^tm1Uboe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207445
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A humanized renilla green fluorescent protein reporter construct (transneuronal tracer truncated barley lectin, IRES, hrGFP and self-excising neomycin resistance cassette) replaced the entire coding sequence. The final allele lacks the resistance cassette. Immunohistochemistry confirmed the absence of transcript expression in vallate papillae. (J:207445)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tas2r131 Mutation: 21 strains or lines available

References

• Original: J:207445 Voigt A, et al., Genetic labeling of Tas1r1 and Tas2r131 taste receptor cells in mice. Chem Senses. 2012 Nov;37(9):897-911
• All: 3 reference(s)