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Tdrd12tm1Yam
Targeted Allele Detail
Summary
Symbol: Tdrd12tm1Yam
Name: tudor domain containing 12; targeted mutation 1, Shinya Yamanaka
MGI ID: MGI:5556124
Gene: Tdrd12  Location: Chr7:35168523-35237170 bp, - strand  Genetic Position: Chr7, 21.37 cM, cytoband B1
Alliance: Tdrd12tm1Yam page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202012
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    Exons 3 and 4 were replaced with a beta-geo cassette by promoter trap selection. (J:202012)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tdrd12 Mutation:  64 strains or lines available
References
Original:  J:202012 Pandey RR, et al., Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16492-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory