Gt(ROSA)26Sor^tm4Dwi
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm4Dwi
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Douglas J Winton
• MGI ID: MGI:5555869
• Synonyms: R26^[CA]30EYFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm4Dwi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202689
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into the locus an EYFP reporter gene with CA30 dinucleotide repeat between the translational start site and remaining coding sequence. Replication slippage is required to achieve expression of the reporter. (J:202689)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

Notes

ES cell line = B6 1.1 (C57BL/6)

References

• Original: J:202689 Kozar S, et al., Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas. Cell Stem Cell. 2013 Nov 7;13(5):626-33
• All: 2 reference(s)