Kdm6b^tm1Iwam
Targeted Allele Detail

Summary

• Symbol: Kdm6b^tm1Iwam
• Name: KDM1 lysine (K)-specific demethylase 6B; targeted mutation 1, Naoki Iwamori
• MGI ID: MGI:5551612
• Gene: Kdm6b Location: Chr11:69289334-69304501 bp, - strand Genetic Position: Chr11, 42.6 cM
• Alliance: Kdm6b^tm1Iwam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206350
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 14. An additional loxP site was inserted downstream of 21. (J:206350)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm6b Mutation: 65 strains or lines available

References

• Original: J:206350 Iwamori N, et al., H3K27 demethylase, JMJD3, regulates fragmentation of spermatogonial cysts. PLoS One. 2013;8(8):e72689
• All: 1 reference(s)