Foxl2tm1.1(cre/ERT2)Kliu
Targeted Allele Detail
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Symbol: |
Foxl2tm1.1(cre/ERT2)Kliu |
Name: |
forkhead box L2; targeted mutation 1.1, Kui Liu |
MGI ID: |
MGI:5548141 |
Synonyms: |
Foxl2-CreERT2 |
Gene: |
Foxl2 Location: Chr9:98837660-98840179 bp, + strand Genetic Position: Chr9, 51.41 cM, cytoband E4
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Alliance: |
Foxl2tm1.1(cre/ERT2)Kliu page
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Germline Transmission: |
Earliest citation of germline transmission:
J:206011
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Parent Cell Line: |
iTL BA1 (ES Cell)
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Strain of Origin: |
(C57BL/6NTac x 129S6/SvEvTac)F1
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Foxl2tm1.1(cre/ERT2)Kliu expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: Homologous recombination was employed to insert an IRES-cre/ERT2-Frt-neo-Frt cassette 259 bp downstream of the stop codon of the Foxl2 gene. Chimeras were bred to C57BL/6 mice, and F1 animals were crossed to flp-expressing mice to delete the neo marker.
(J:206011)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Foxl2
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Foxl2 Mutation: |
15 strains or lines available
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Original: |
J:206011 Zheng W, et al., Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions. Hum Mol Genet. 2014 Feb 15;23(4):920-8 |
All: |
6 reference(s) |
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