Spink1tm3(cre)Kymm
Targeted Allele Detail
|
Symbol: |
Spink1tm3(cre)Kymm |
Name: |
serine peptidase inhibitor, Kazal type 1; targeted mutation 3, Ken-ichi Yamamura |
MGI ID: |
MGI:5544431 |
Synonyms: |
Spink3cre |
Gene: |
Spink1 Location: Chr18:43861134-43870302 bp, - strand Genetic Position: Chr18, 23.47 cM, cytoband B3
|
Alliance: |
Spink1tm3(cre)Kymm page
|
|
|
Allele Type: |
|
Targeted (Recombinase) |
Mutation: |
|
Insertion
|
|
|
Spink1tm3(cre)Kymm expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Spink1 (MGI:106202) |
|
|
|
|
Mutation details: A loxJTZ17 site was inserted at the 5' end of a cassette containing the NLS-cre-polyA sequence (nuclear localization signal-cre recombinase-polyadenylation signal). A PGK-puromycin selection cassett and a lox2272 site was inserted at the 3' end of the targeting construct. Targeted recombination in ES cells already containing Spink3tm1Kymm inserted the cre cassette upstream of exon 1 of Spink3, replacing the neo marker. Chimeras were produced from correctly targeted ES cell clones and germline transmission was established by crosses to C57BL6/J animals.
(J:205182)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Spink1
(mouse)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Spink1 Mutation: |
13 strains or lines available
|
|
Original: |
J:205182 Sakata K, et al., Generation and analysis of serine protease inhibitor kazal type 3-cre driver mice. Exp Anim. 2014;63(1):45-53 |
All: |
4 reference(s) |
|