Chad^tm1Gast
Targeted Allele Detail

Summary

• Symbol: Chad^tm1Gast
• Name: chondroadherin; targeted mutation 1, Gunhild A Stordalen
• MGI ID: MGI:5529270
• Gene: Chad Location: Chr11:94455873-94459953 bp, + strand Genetic Position: Chr11, 58.9 cM
• Alliance: Chad^tm1Gast page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203141
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance cassette was inserted into the gene. Western blot analysis confirmed the absence of protein expression in the trachea, nasal cartilage and knee cartilage. (J:203141)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chad Mutation: 16 strains or lines available

References

• Original: J:203141 Hessle L, et al., The skeletal phenotype of chondroadherin deficient mice. PLoS One. 2013;8(6):e63080
• All: 2 reference(s)