Psme4^tm1Tchi
Targeted Allele Detail

Summary

• Symbol: Psme4^tm1Tchi
• Name: proteasome (prosome, macropain) activator subunit 4; targeted mutation 1, Tomoki Chiba
• MGI ID: MGI:5521286
• Gene: Psme4 Location: Chr11:30721726-30830361 bp, + strand Genetic Position: Chr11, 18.16 cM
• Alliance: Psme4^tm1Tchi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197675
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 25 and 26. (J:197675)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Psme4 Mutation: 96 strains or lines available

References

• Original: J:197675 Qian MX, et al., Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis. Cell. 2013 May 23;153(5):1012-24
• All: 3 reference(s)