Gt(ROSA)26Sor^{tm1(CAG-neo,-HTB)Fhg}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-neo,-HTB)Fhg}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Fred H Gage
• MGI ID: MGI:5518925
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-neo,-HTB)Fhg} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197432
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter) Mutation: Insertion Mutation details: A floxed PGK-neo and stop codon were place under the control of a CAG promoter and followed by a tricistronic insert composed of a histone tagged GFP, the avian sarcoma leucosis virus glycoprotein (EnvA) receptor (TVA), and the rabies glycoprotein B19G. The tricistronic insert is only expressed after cre excision of thge PGK-neo sequence and its stop codon. (J:197432)

Generation of the Gt(ROSA)26Sor^tm1(CAG-neo,-HTB)Fhg allele

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:197432 Li Y, et al., Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9106-11
• All: 17 reference(s)