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Chemically induced Allele Detail
Symbol: Slc45a2uw-8Btlr
Name: solute carrier family 45, member 2; underwhite 8 Bruce Beutler
MGI ID: MGI:5515378
Synonyms: cheng
Gene: Slc45a2  Location: Chr15:11000807-11029319 bp, + strand  Genetic Position: Chr15, 5.4 cM
Alliance: Slc45a2uw-8Btlr page
Diluted coat color of a homozygous Slc45a2uw-8Btlr mouse

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
Mutation detailsENU mutagenesis induced a T to C transition at base pair 11025868 bp (v38) on chromosome 15 in the GenBank genomic region NC_000081. The mutation corresponds to residue 1399 in the mRNA sequence (NM_053077.3) in exon 6 of 7 total exons. The mutation results in a substitution of serine (S) to a proline (P) at residue 435. (J:201724)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc45a2 Mutation:  44 strains or lines available
Original:  J:201724 Purrington T, et al., Direct data submission for cheng. MGI Direct Data Submission. 2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory