Baz1b^MommeD16
Chemically induced Allele Detail

Summary

• Symbol: Baz1b^MommeD16
• Name: bromodomain adjacent to zinc finger domain, 1B; modifier of murine metastable epialleles, D16
• MGI ID: MGI:5515363
• Gene: Baz1b Location: Chr5:135216118-135274983 bp, + strand Genetic Position: Chr5, 75.05 cM
• Alliance: Baz1b^MommeD16 page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: A T-to-C single point mutation in exon 2 is predicted to result in a L75P amino acid substitution in the encoded protein. Reduced amounts of encoded protein were detected on Western blot of embryonic tissue, suggesting that this allele is hypomorphic. (J:201508)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Baz1b Mutation: 80 strains or lines available

References

• Original: J:201508 Daxinger L, et al., An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Genome Biol. 2013 Sep 11;14(9):R96
• All: 1 reference(s)