Dcx^{tm1(HBEGF)Pfba}
Targeted Allele Detail

Summary

• Symbol: Dcx^{tm1(HBEGF)Pfba}
• Name: doublecortin; targeted mutation 1, Perry F Bartlett
• MGI ID: MGI:5514501
• Synonyms: DCX^DTR
• Gene: Dcx Location: ChrX:142638838-142716307 bp, - strand Genetic Position: ChrX, 64.89 cM
• Alliance: Dcx^{tm1(HBEGF)Pfba} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196669
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Dcx^{tm1(HBEGF)Pfba} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HBEGF (1839)

  Hbegf

  (MGI:96070)

• Mutation details: An IRES-Venus-HBEGF (human diphtheria toxin receptor) inserted downstream of the stop codon in exon 7. The fluorescence gene is nonfuctional. (J:196669)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dcx Mutation: 18 strains or lines available

References

• Original: J:196669 Vukovic J, et al., Immature doublecortin-positive hippocampal neurons are important for learning but not for remembering. J Neurosci. 2013 Apr 10;33(15):6603-13
• All: 3 reference(s)