Cnih3^tm1.1Ran
Targeted Allele Detail

Summary

• Symbol: Cnih3^tm1.1Ran
• Name: cornichon family AMPA receptor auxiliary protein 3; targeted mutation 1.1, Roger A Nicoll
• MGI ID: MGI:5513018
• Synonyms: Cnih3^fl
• Gene: Cnih3 Location: Chr1:181180193-181288206 bp, + strand Genetic Position: Chr1, 84.53 cM, cytoband H4
• Alliance: Cnih3^tm1.1Ran page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197912
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 4. Flp-mediated recombination removed the neomycin resistance cassette. (J:197912)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cnih3 Mutation: 15 strains or lines available

References

• Original: J:197912 Herring BE, et al., Cornichon proteins determine the subunit composition of synaptic AMPA receptors. Neuron. 2013 Mar 20;77(6):1083-96
• All: 1 reference(s)