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Targeted Allele Detail
Symbol: Ctdnep1tm2Ryn
Name: CTD nuclear envelope phosphatase 1; targeted mutation 2, Ryuichi Nishinakamura
MGI ID: MGI:5510831
Synonyms: DullardLacZ
Gene: Ctdnep1  Location: Chr11:69871994-69881427 bp, + strand  Genetic Position: Chr11, 42.95 cM, cytoband B4
Alliance: Ctdnep1tm2Ryn page
Germline Transmission:  Earliest citation of germline transmission: J:199855
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe targeted construct replaced the coding sequence in exon 1 through exon 4 with a lox71 site, lacZ reporter gene, polyadenylation sequence, FRT site, neomycin resistance cassette, FRT site, loxP site and polyadenylation sequence. Q-PCR confirmed the absence of transcript expression in E7.5 embryos. (J:199855)
Generation of the Ctdnep1tm2Ryn allele
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 8 assay results
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ctdnep1 Mutation:  16 strains or lines available
Original:  J:199855 Tanaka SS, et al., Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo. PLoS One. 2013;8(3):e57428
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory