Tg(tetO-AIMP2)630Tmd
Transgene Detail

Summary

• Symbol: Tg(tetO-AIMP2)630Tmd
• Name: transgene insertion 630, Ted M Dawson
• MGI ID: MGI:5506893
• Transgene: Tg(tetO-AIMP2)630Tmd Location: unknown
• Alliance: Tg(tetO-AIMP2)630Tmd page

Transgene origin

• Strain of Origin: B6C3F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-AIMP2)630Tmd expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AIMP2 (7965)

  Aimp2

  (MGI:2385237)

• Tg(tetO-AIMP2)630Tmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	tetO

• Mutation details: The C-terminal FLAG-tagged human aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 (AIMP2) gene was placed under control of a tetO promoter. (J:200063)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:200063 Lee Y, et al., Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nat Neurosci. 2013 Oct;16(10):1392-400
• All: 1 reference(s)