Hopx^tm3.1Joe
Targeted Allele Detail

Summary

• Symbol: Hopx^tm3.1Joe
• Name: HOP homeobox; targeted mutation 3.1, Jonathan A Epstein
• MGI ID: MGI:5502918
• Synonyms: Hopx^3XFlag
• Gene: Hopx Location: Chr5:77234835-77262968 bp, - strand Genetic Position: Chr5, 41.45 cM
• Alliance: Hopx^tm3.1Joe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195123
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 3XFlag sequence followed by a GFP and an Frt flanked neomycin cassette were appended to exon 3. Subsequent expression of flp recombinase excised the selection cassette. (J:195123)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hopx Mutation: 11 strains or lines available

References

• Original: J:195123 Takeda N, et al., Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Development. 2013 Apr;140(8):1655-64
• All: 13 reference(s)