Alx4^M1Yzcm
Chemically induced Allele Detail

Summary

• Symbol: Alx4^M1Yzcm
• Name: aristaless-like homeobox 4; mutation 1, Yangzhou University Comparative Medicine Center
• MGI ID: MGI:5502864
• Gene: Alx4 Location: Chr2:93472779-93511686 bp, + strand Genetic Position: Chr2, 51.62 cM
• Alliance: Alx4^M1Yzcm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a A to T transversion mutation that resulted in substitution of a lysine codon with a stop (nonsense) codon at position 145 (K145X). (J:199512)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alx4 Mutation: 20 strains or lines available

References

• Original: J:199512 Chen B, et al., Multiple abnormalities due to a nonsense mutation in the Alx4 gene. Genet Mol Res. 2013;12(3):2771-8
• All: 1 reference(s)