Gbx1^tm1Stwt
Targeted Allele Detail

Summary

• Symbol: Gbx1^tm1Stwt
• Name: gastrulation brain homeobox 1; targeted mutation 1, Samuel T Waters
• MGI ID: MGI:5502433
• Synonyms: Gbx1^flox
• Gene: Gbx1 Location: Chr5:24709424-24731846 bp, - strand Genetic Position: Chr5, 11.93 cM
• Alliance: Gbx1^tm1Stwt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197199
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. (J:197199)

Generation of Gbx1^tm1Stwt allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gbx1 Mutation: 19 strains or lines available

References

• Original: J:197199 Buckley DM, et al., Characterization of the Gbx1-/- mouse mutant: a requirement for Gbx1 in normal locomotion and sensorimotor circuit development. PLoS One. 2013;8(2):e56214
• All: 1 reference(s)