Tg(LRRK2*G2019S)2AMjff
Transgene Detail
|
Symbol: |
Tg(LRRK2*G2019S)2AMjff |
Name: |
transgene insertion 2A, The Michael J Fox Foundation |
MGI ID: |
MGI:5502368 |
Synonyms: |
Tg(LRRK2*G2019S)2AGrsr |
Transgene: |
Tg(LRRK2*G2019S)2AMjff Location: Chr2:80726749-80726750 bp Genetic Position: Chr2, Syntenic
|
Alliance: |
Tg(LRRK2*G2019S)2AMjff page
|
|
|
Transgene Type: |
|
Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutations: |
|
Insertion, Nucleotide substitutions
|
|
|
Tg(LRRK2*G2019S)2AMjff expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
LRRK2 (120892) |
|
|
|
|
|
Mutation details: A 188 kb bacterial artificial chromosome (BAC) containing the entire human LRRK2 (leucine-rich repeat kinase 2) gene was modified by targeted mutation of the LRRK2 locus to harbor the LRRK2 G2019S mutation associated with autosomal dominant, late-onset Parkinson's disease originally identified in Spanish families originating from the Basque region.
(J:101977)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
All: |
7 reference(s) |
|