Tg(Ucp1-HBEGF/GFP)445Biat
Transgene Detail

Summary

• Symbol: Tg(Ucp1-HBEGF/GFP)445Biat
• Name: transgene insertion 445, Biomodels Austria
• MGI ID: MGI:5498649
• Synonyms: Tg(Ucp1-GFP)445Biat, Ucp1-GFP
• Transgene: Tg(Ucp1-HBEGF/GFP)445Biat Location: unknown
• Alliance: Tg(Ucp1-HBEGF/GFP)445Biat page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Ucp1-HBEGF/GFP)445Biat expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  monkey	HBEGF

• Mutation details: Sequences encoding a primate heparin-binding epidermal growth factor (HB-EGF)/enhanced GFP fusion protein, an Frt-flanked neo/kanamycin resistance cassette and a polyadenylation signal were inserted by recombineering into a BAC vector containing the Ucp1 promoter. The purified BAC construct was injected into C57BL/6N fertilized oocytes. Line 445 was established. These mice were crossed to Tg(ACTBFLPe)9205Dym mice to excise the resistance cassette. (J:198491)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:198491 Rosenwald M, et al., Bi-directional interconversion of brite and white adipocytes. Nat Cell Biol. 2013 Jun;15(6):659-67
• All: 6 reference(s)