Dcaf4tm1e(EUCOMM)Hmgu
Targeted Allele Detail
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Symbol: |
Dcaf4tm1e(EUCOMM)Hmgu |
Name: |
DDB1 and CUL4 associated factor 4; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:5497199 |
Gene: |
Dcaf4 Location: Chr12:83567240-83588694 bp, + strand Genetic Position: Chr12, 38.75 cM, cytoband D3
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IMPC: |
Dcaf4 gene page |
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Mutant Cell Lines: |
HEPD0855_8_A05, HEPD0855_8_A08, HEPD0855_8_B05, HEPD0855_8_B06, HEPD0855_8_C05, HEPD0855_8_C06, HEPD0855_8_C08, HEPD0855_8_D05, HEPD0855_8_D07, HEPD0855_8_D08, HEPD0855_8_E05, HEPD0855_8_E06, HEPD0855_8_F05, HEPD0855_8_F07, HEPD0855_8_F08, HEPD0855_8_G06, HEPD0855_8_G07, HEPD0855_8_H06, HEPD0855_8_H07, HEPD0855_8_H08 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8.N4 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Bact_P cassette was inserted at position 83575206 of Chromosome 12 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
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Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
1 reference(s) |
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