B4galt4tm1e(EUCOMM)Hmgu
Targeted Allele Detail
|
Symbol: |
B4galt4tm1e(EUCOMM)Hmgu |
Name: |
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:5497065 |
Gene: |
B4galt4 Location: Chr16:38562626-38589411 bp, + strand Genetic Position: Chr16, 26.87 cM, cytoband B4
|
IMPC: |
B4galt4 gene page |
|
Mutant Cell Lines: |
HEPD0862_1_B05, HEPD0862_1_C05, HEPD0862_1_C07, HEPD0862_1_C08, HEPD0862_1_D07, HEPD0862_1_E05, HEPD0862_1_G07, HEPD0862_1_G08, HEPD0862_1_H08 |
Germline Transmission: |
Unknown
|
Parent Cell Line: |
JM8A3.N1 (ES Cell)
|
Strain of Origin: |
C57BL/6N-Atm1Brd
|
Project Collection: |
EUCOMM
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutation: |
|
Insertion
Vector: L1L2_GT1_LF2A_LacZ_BetactP_neo
|
|
|
Mutation details: The L1L2_GT1_LF2A_LacZ_BetactP_neo cassette was inserted at position 38573878 of Chromosome 16 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
|
|
|
|
Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
1 reference(s) |
|