Prkg1^tm1.1Pfe
Targeted Allele Detail

Summary

• Symbol: Prkg1^tm1.1Pfe
• Name: protein kinase, cGMP-dependent, type I; targeted mutation 1.1, Alexander Pfeifer
• MGI ID: MGI:5496128
• Synonyms: PKGI^fl
• Gene: Prkg1 Location: Chr19:30541889-31742433 bp, - strand Genetic Position: Chr19, 25.17 cM, cytoband C2
• Alliance: Prkg1^tm1.1Pfe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199222
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A floxed allele with a neo cassette was generated. (J:199222)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkg1 Mutation: 58 strains or lines available

References

• Original: J:199222 Haas B, et al., Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis. Sci Signal. 2009;2(99):ra78
• All: 3 reference(s)