Tg(CAG-tTS)1Mlit
Transgene Detail

Summary

• Symbol: Tg(CAG-tTS)1Mlit
• Name: transgene insertion 1, Jian Fei
• MGI ID: MGI:5496007
• Synonyms: CAG-tTS
• Transgene: Tg(CAG-tTS)1Mlit Location: unknown
• Alliance: Tg(CAG-tTS)1Mlit page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The CAG promoter drives ubiquitous expression of the transcriptional repressor molecule (tetR) fused to the KRAB domain of human ZNF10 followed by a polyadenylation sequence. This transgene allows for inducible and reversable regulation of an endogenous gene containing the inserted tetracycline response element. Four lines were generated, including line tTS. (J:196015)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:196015 Sun R, et al., Inducible and reversible regulation of endogenous gene in mouse. Nucleic Acids Res. 2012 Nov;40(21):e166
• All: 2 reference(s)