Hdac1^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Hdac1^tm1.1Mrl
• Name: histone deacetylase 1; targeted mutation 1.1, Merck Research Laboratory
• MGI ID: MGI:5494616
• Synonyms: Hdac1^L, Hdac1^tm1Ics
• Gene: Hdac1 Location: Chr4:129409897-129436506 bp, - strand Genetic Position: Chr4, 63.26 cM
• Alliance: Hdac1^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197818
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 is floxed. (J:197818)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hdac1 Mutation: 36 strains or lines available

References

• Original: J:197818 Wilting RH, et al., Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis. EMBO J. 2010 Aug 4;29(15):2586-97
• All: 4 reference(s)