Gtf2i^tm1Lro
Targeted Allele Detail

Summary

• Symbol: Gtf2i^tm1Lro
• Name: general transcription factor II I; targeted mutation 1, L Osborne
• MGI ID: MGI:5490967
• Synonyms: Gtf2i^3'UTRloxP
• Gene: Gtf2i Location: Chr5:134266688-134343614 bp, - strand Genetic Position: Chr5, 74.48 cM
• Alliance: Gtf2i^tm1Lro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196809
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• A loxP site was inserted into the 3'UTR downstream of exon 34. (J:196809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gtf2i Mutation: 138 strains or lines available

References

• Original: J:196809 Mervis CB, et al., Duplication of GTF2I results in separation anxiety in mice and humans. Am J Hum Genet. 2012 Jun 8;90(6):1064-70
• All: 1 reference(s)