Fgf21^tm1.2Djm
Targeted Allele Detail

Summary

• Symbol: Fgf21^tm1.2Djm
• Name: fibroblast growth factor 21; targeted mutation 1.2, David J Mangelsdorf
• MGI ID: MGI:5486224
• Synonyms: Fgf21^loxP
• Gene: Fgf21 Location: Chr7:45263314-45264914 bp, - strand Genetic Position: Chr7, 29.38 cM, cytoband B2
• Alliance: Fgf21^tm1.2Djm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 1, followed by a second loxP site and a frt-flanked neomycin resistance (neo) cassette downstream of exon 3. Flp-mediated recombination removed the neo cassette. (J:150831)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgf21 Mutation: 22 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 52 reference(s)