Hnf1b^tm1Ics
Targeted Allele Detail

Summary

• Symbol: Hnf1b^tm1Ics
• Name: HNF1 homeobox B; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:5471835
• Gene: Hnf1b Location: Chr11:83741035-83796743 bp, + strand Genetic Position: Chr11, 51.23 cM
• Alliance: Hnf1b^tm1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194051
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted flanking exon 4 via homologous recombination. (J:194051)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hnf1b Mutation: 16 strains or lines available

References

• Original: J:194051 Heliot C, et al., HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85
• All: 5 reference(s)