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Targeted Allele Detail
Symbol: Pld2tm1Yaka
Name: phospholipase D2; targeted mutation 1, Yasunori Kanaho
MGI ID: MGI:5468333
Gene: Pld2  Location: Chr11:70430890-70448936 bp, + strand  Genetic Position: Chr11, 42.99 cM
Alliance: Pld2tm1Yaka page
Germline Transmission:  Earliest citation of germline transmission: J:192844
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 14 and 15 were replaced with a floxed neo cassette. Western blot analysis confirmed the absence of protein expression. (J:192844)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pld2 Mutation:  33 strains or lines available
Original:  J:192844 Sato T, et al., Molecular mechanisms of N-formyl-methionyl-leucyl-phenylalanine-induced superoxide generation and degranulation in mouse neutrophils: phospholipase D is dispensable. Mol Cell Biol. 2013 Jan;33(1):136-45
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory