Tg(Nphs1-cre)#Seq
Transgene Detail

Summary

• Symbol: Tg(Nphs1-cre)#Seq
• Name: transgene insertion, Susan E Quaggin
• MGI ID: MGI:5468313
• Synonyms: Nphs1-Cre, Pod-Cre, Podocin-Cre
• Transgene: Tg(Nphs1-cre)#Seq Location: unknown
• Alliance: Tg(Nphs1-cre)#Seq page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Nphs1-cre)#Seq expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nphs1 (MGI:1859637)

• Mutation details: A mouse Neph1 promoter fused to a cre recombinase gene was used for the transgene. A 4.125 kb fragment of the mouse Neph1 promoter was used to drive transgene expression in podocytes. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:82024)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nphs1 (mouse) Summary of all recombinase alleles driven by Nphs1. Alliance mouse Nphs1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:193210 Jin J, et al., Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function. Cell. 2012 Oct 12;151(2):384-99
• All: 6 reference(s)