About   Help   FAQ
Cx3cr1tm1.1(cre)Jung
Targeted Allele Detail
Summary
Symbol: Cx3cr1tm1.1(cre)Jung
Name: C-X3-C motif chemokine receptor 1; targeted mutation 1.1, Steffen Jung
MGI ID: MGI:5467983
Synonyms: Cx3cr1cre
Gene: Cx3cr1  Location: Chr9:119877749-119897362 bp, - strand  Genetic Position: Chr9, 71.37 cM
Alliance: Cx3cr1tm1.1(cre)Jung page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193038
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Cx3cr1tm1.1(cre)Jung expression driven by 1 gene
 
Mutation detailsA cre recombinase cassette with a floxed neo was introduced into a BAC by RedE/T recombineering, replacing the coding exon, prior to homologous recombination to target the gene in ES cells. Cre-mediated recombination removed the selection cassette. (J:193038)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cx3cr1 (mouse)
Summary of all recombinase alleles driven by Cx3cr1.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cx3cr1 Mutation:  45 strains or lines available
References
Original:  J:193038 Yona S, et al., Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis. Immunity. 2013 Jan 24;38(1):79-91
All:  115 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory