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Tg(Slc16a1-luc)50Rttr
Transgene Detail
Summary
Symbol: Tg(Slc16a1-luc)50Rttr
Name: transgene insertion 50, Guy Rutter
MGI ID: MGI:5465430
Synonyms: Mct1-Luc
Transgene: Tg(Slc16a1-luc)50Rttr  Location: unknown  
Alliance: Tg(Slc16a1-luc)50Rttr page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe murine Mct1 coding sequence was amplified from pUC18-Mct1, with the addition of a single COOH-terminal c-Myc epitope tag by PCR (primer sequences in Supplementary Table 1), and inserted between the NheI and EcoRV sites of plasmid pBI-L Tet (Clontech). This generated a plasmid with a bidirectional tetracycline-regulated promoter driving expression of both Mct1::Myc and firefly luciferase. Lines 28, 50 and 60 were generated. (J:192583)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:192583 Pullen TJ, et al., Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic beta-cells leads to relative hyperinsulinism during exercise. Diabetes. 2012 Jul;61(7):1719-25
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory