Bcl6^tm1.1Cdon
Targeted Allele Detail

Summary

• Symbol: Bcl6^tm1.1Cdon
• Name: B cell leukemia/lymphoma 6; targeted mutation 1.1, Chen Dong
• MGI ID: MGI:5464903
• Synonyms: bcl6^rfp
• Gene: Bcl6 Location: Chr16:23783802-23807602 bp, - strand Genetic Position: Chr16, 15.26 cM
• Alliance: Bcl6^tm1.1Cdon page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191271
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

Allele Type: Targeted (Reporter) Mutation: Insertion Mutation details: An FRT-flanked neo cassette, IRES, RFP and polyadenylation sequence were inserted into the 3'UTR. Flp-mediated recombination removed the neo cassette. (J:191271)

Generation of the Bcl6^tm1.1Cdon allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl6 Mutation: 59 strains or lines available

References

• Original: J:191271 Liu X, et al., Bcl6 expression specifies the T follicular helper cell program in vivo. J Exp Med. 2012 Sep 24;209(10):1841-52, S1-24
• All: 8 reference(s)