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Vps52tm1.1Kab
Targeted Allele Detail
Summary
Symbol: Vps52tm1.1Kab
Name: VPS52 GARP complex subunit; targeted mutation 1.1, Kuniya Abe
MGI ID: MGI:5463589
Synonyms: Vps52flox
Gene: Vps52  Location: Chr17:34174786-34186009 bp, + strand  Genetic Position: Chr17, 17.98 cM
Alliance: Vps52tm1.1Kab page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:190873
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site and FRT flanked pgk-neo cassette were inserted in intron 1 and a loxP site was inserted in intron 2 via homologous recombination. Flp mediated recombination removed the pgk-neo cassette. (J:190873)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vps52 Mutation:  42 strains or lines available
References
Original:  J:190873 Sugimoto M, et al., Molecular identification of t(w5): Vps52 promotes pluripotential cell differentiation through cell-cell interactions. Cell Rep. 2012 Nov 29;2(5):1363-74
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/01/2024
MGI 6.24
The Jackson Laboratory