Cyp2s1^tm1Ding
Targeted Allele Detail

Summary

• Symbol: Cyp2s1^tm1Ding
• Name: cytochrome P450, family 2, subfamily s, polypeptide 1; targeted mutation 1, Xinxin Ding
• MGI ID: MGI:5449902
• Gene: Cyp2s1 Location: Chr7:25501894-25515950 bp, - strand Genetic Position: Chr7, 14.05 cM
• Alliance: Cyp2s1^tm1Ding page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190445
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with a hygromycin resistance gene cassette and loxP site via homologous recombination. (J:190445)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cyp2s1 Mutation: 23 strains or lines available

References

• Original: J:190445 Wei Y, et al., Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model. Drug Metab Dispos. 2013 Jan;41(1):132-40
• All: 2 reference(s)