Pnmt^tm2.1Sne
Targeted Allele Detail

Summary

• Symbol: Pnmt^tm2.1Sne
• Name: phenylethanolamine-N-methyltransferase; targeted mutation 2.1, Steven N Ebert
• MGI ID: MGI:5449442
• Synonyms: Pnmt^nEGFP, Pnmt::nEGFP
• Gene: Pnmt Location: Chr11:98277449-98279006 bp, + strand Genetic Position: Chr11, 61.75 cM, cytoband D
• Alliance: Pnmt^tm2.1Sne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190425
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An EGFP with a nuclear localization sequence and an FRT-flanked neo cassette were inserted into exon 1 to create an in-frame fusion. Flp-mediated recombination removed the neo cassette. (J:190425)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pnmt Mutation: 12 strains or lines available

References

• Original: J:190425 Xia J, et al., Targeting of the enhanced green fluorescent protein reporter to adrenergic cells in mice. Mol Biotechnol. 2013 Jun;54(2):350-60
• All: 3 reference(s)