Stx4a^tm2Jpes
Targeted Allele Detail

Summary

• Symbol: Stx4a^tm2Jpes
• Name: syntaxin 4A (placental); targeted mutation 2, Jeffrey E Pessin
• MGI ID: MGI:5445557
• Synonyms: Stx4a^tm1Jepn, Syntaxin-4^flox
• Gene: Stx4a Location: Chr7:127439832-127450160 bp, + strand Genetic Position: Chr7, 69.77 cM, cytoband F4
• Alliance: Stx4a^tm2Jpes page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189176
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted into intron 1 and 4. (J:189176)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stx4a Mutation: 20 strains or lines available

References

• Original: J:189176 Ye S, et al., Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion. Blood. 2012 Sep 20;120(12):2484-92
• All: 1 reference(s)