Tg(Adam12-tTA,-HBEGF)1Lpe
Transgene Detail
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Symbol: |
Tg(Adam12-tTA,-HBEGF)1Lpe |
Name: |
transgene insertion 1, Lucie Peduto |
MGI ID: |
MGI:5442697 |
Synonyms: |
Adam12-tTA-ires-DtrTG, M12-tTA |
Transgene: |
Tg(Adam12-tTA,-HBEGF)1Lpe Location: unknown
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Alliance: |
Tg(Adam12-tTA,-HBEGF)1Lpe page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inserted expressed sequence, Transactivator) |
Mutation: |
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Insertion
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Tg(Adam12-tTA,-HBEGF)1Lpe expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
HBEGF (1839) |
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Mutation details: A tTA-ires-HBEGF (tTA-ires-DTR) coding sequence, including a polyA sequence was inserted into exon 1 of the Adam12 gene in a 200 kb BAC by homologous recombination. The sequence replaced the endogenous ATG translation start codon. The modified BAC was used to generate transgenic founders. Line information is not available.
(J:188912)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:188912 Dulauroy S, et al., Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat Med. 2012 Aug;18(8):1262-70 |
All: |
1 reference(s) |
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