Gt(ROSA)26Sor^{tm1(CAG-EGFP,-mCerulean,-mOrange,-mCherry)Ilw}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-EGFP,-mCerulean,-mOrange,-mCherry)Ilw}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Irving L Weissman
• MGI ID: MGI:5441200
• Synonyms: R26^VT2/GK3, Rosa26-Rainbow, Rosa26^rbw, ROSA26R^rb
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-EGFP,-mCerulean,-mOrange,-mCherry)Ilw} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158886
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The expression construct contains a ubiquitous CAG promoter, lox2272 site, loxN site, loxP site, EGFP, lox2272 site, mCerulean, loxN site, mOrange, loxP site and mCherry. While EGFP expression is constitutive, the remaining reporters are only expressed following cre-mediated recombination. (J:188630)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:158886 Red-Horse K, et al., Coronary arteries form by developmental reprogramming of venous cells. Nature. 2010 Mar 25;464(7288):549-53
• All: 38 reference(s)