Tg(Hoxa4-cre)2Jlzn
Transgene Detail

Summary

• Symbol: Tg(Hoxa4-cre)2Jlzn
• Name: transgene insertion 2, Jeffrey Lorenz Neul
• MGI ID: MGI:5440715
• Synonyms: HoxA4^Cre, Tg(Hoxa4-cre)2Hzo
• Transgene: Tg(Hoxa4-cre)2Jlzn Location: unknown
• Alliance: Tg(Hoxa4-cre)2Jlzn page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hoxa4-cre)2Jlzn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Hoxa4

• Mutation details: A construct was generated that consisted of the Hoxa4 enhancer/promoter (including exon 1 and part of exon 2) with cre recombinase sequence fused in-frame with Hoxa4 at exon2, and a polyadenylation signal. The transgene was injected into pronuclei to generate two transgenic lines. Both lines were maintained and line 2 was analyzed in detail. (J:188329)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hoxa4 (species not specified) Summary of all recombinase alleles driven by Hoxa4.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:188329 Huang WH, et al., Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness at Birth and Chemoresponsiveness in Adulthood. Neuron. 2012 Sep 6;75(5):799-809
• All: 5 reference(s)