Tenm4^{Tg(Col2a1-Hspg2)2Yoya}
Transgenic Allele Detail

Summary

• Symbol: Tenm4^{Tg(Col2a1-Hspg2)2Yoya}
• Name: teneurin transmembrane protein 4; transgene insertion 2, Yoshihiko Yamada
• MGI ID: MGI:5440486
• Synonyms: fur, furue, furue^Tg(Hspg2)2Yy, Perl^tg
• Gene: Tenm4 Location: Chr7:95820453-96560300 bp, + strand Genetic Position: Chr7, 52.53 cM
• Alliance: Tenm4^{Tg(Col2a1-Hspg2)2Yoya} page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Null/knockout)
• Mutations: Duplication, Insertion
• Tenm4^{Tg(Col2a1-Hspg2)2Yoya} involves 1 genes/genome features (Tenm4) View all
• Mutation details: The promoter drives expression of the FLAG-tagged cDNA in cartilage. In line 2, the transgene inserted between exon 5 and 6, resulting in a 3 kb duplication. RT-PCR confirmed the absence of transgene expression in the central nervous system. Western blot analysis confirmed the absence of endogenous protein expression in the spinal cord. (J:187705)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tenm4 Mutation: 300 strains or lines available

References

• Original: J:187705 Suzuki N, et al., Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS. J Neurosci. 2012 Aug 22;32(34):11586-99
• All: 5 reference(s)