Ids^tm1Eto
Targeted Allele Detail

Summary

• Symbol: Ids^tm1Eto
• Name: iduronate 2-sulfatase; targeted mutation 1, Yoshikatsu Eto
• MGI ID: MGI:5439833
• Gene: Ids Location: ChrX:69386675-69408690 bp, - strand Genetic Position: ChrX, 36.01 cM
• Alliance: Ids^tm1Eto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188058
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 2 through 5 were deleted, creating a knock-out allele. (J:188058)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ids Mutation: 11 strains or lines available

References

• Original: J:188058 Higuchi T, et al., Enzyme replacement therapy (ERT) procedure for mucopolysaccharidosis type II (MPS II) by intraventricular administration (IVA) in murine MPS II. Mol Genet Metab. 2012 Sep;107(1-2):122-8
• All: 4 reference(s)